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| MDL® Toxicity Database |
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MDL Toxicity Database is a structure-searchable bioactivity database of toxic chemical substances. An Oracle-based system accessible through MDL ISIS/Host or DiscoveryGate, MDL Toxicity Database contains data from in vivo and in vitro studies of acute toxicity, mutagenicity, skin and eye irritation, tumorigenicity and carcinogenicity, reproductive effects and multiple dose effects. Information covered includes species of organism studied, tissue studied, route of administration, dose, endpoint, toxic effects descriptors, severity of response, CAS Registry Numbers, Beilstein Registry Numbers, chemical names and synonyms, molecular formula and molecular weight. The Toxicity database includes references to the original publications reporting the toxicity data and to relevant review articles when applicable.
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Chemical record
For every chemical record retrieved from a search of MDL Toxicity, this form displays chemical structure and general compound identifiers such as chemical names and synonyms, CAS Registry Number, and other important external registry numbers.
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Toxicity data and literature citation
For each category of toxicity data (in this case, Acute Toxicity) the form displays experimental data and the relevant citation from the original literature. Users scroll through data for each literature citation individually.
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Six categories of Toxicity data
Six categories of data (acute toxicity, mutagenicity, skin/eye irritation, tumorigenicity, reproductive effects and multiple does effects) are covered in MDL Toxicity. Displayed here is the thirteenth of 66 records cited for mutagenicity of hydantoin.
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