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Home > MDL® Discovery Predictive Science > MDL® Toxicity Database
 
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MDL Toxicity Database is a structure-searchable bioactivity database of toxic chemical substances. An Oracle-based system accessible through MDL ISIS/Host or DiscoveryGate, MDL Toxicity Database contains data from in vivo and in vitro studies of acute toxicity, mutagenicity, skin and eye irritation, tumorigenicity and carcinogenicity, reproductive effects and multiple dose effects. Information covered includes species of organism studied, tissue studied, route of administration, dose, endpoint, toxic effects descriptors, severity of response, CAS Registry Numbers, Beilstein Registry Numbers, chemical names and synonyms, molecular formula and molecular weight. The Toxicity database includes references to the original publications reporting the toxicity data and to relevant review articles when applicable.

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Chemical record

For every chemical record retrieved from a search of MDL Toxicity, this form displays chemical structure and general compound identifiers such as chemical names and synonyms, CAS Registry Number, and other important external registry numbers.

     
     
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Toxicity data and literature citation

For each category of toxicity data (in this case, Acute Toxicity) the form displays experimental data and the relevant citation from the original literature. Users scroll through data for each literature citation individually.

     
     
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Six categories of Toxicity data

Six categories of data (acute toxicity, mutagenicity, skin/eye irritation, tumorigenicity, reproductive effects and multiple does effects) are covered in MDL Toxicity. Displayed here is the thirteenth of 66 records cited for mutagenicity of hydantoin.

Additional Info

MDL Metabolite/Toxicity brochure (PDF)

MDL Toxicity Database datasheet (PDF)

Overview of Available Databases (PDF)

 
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18-May-08
Symyx Global Symposium 2008: R&D Integration Success
 
22-May-08
Break through in-house capability constraints with Symyx Life Science Research services
 
28-May-08
The impact of automation on the efficiency of laboratory sample preparation and analysis
 
 
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13-May-08
Symyx Speeds Adoption of Symyx Notebook and Other Software Products Through Convenient, Cost-effective Online Training
 
28-Apr-08
Symyx Unveils New Enterprise Electronic Laboratory Notebook
 
22-Apr-08
Symyx to Bring Together Industry Leaders for Symposia to Discuss Future of R&D Integration
 
 
 
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